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Wednesday, July 2, 2008

Laminar Flow Clean Room Products


Clean room hoods like laminar flow hoods have filtration systems controlling airflow and velocity to keep airborne particles from having contact with other objects or particles. Laminar flow clean room hoods help protecting and keep areas sanitary and contaminant –free, retaining the ability to protect samples and laboratory workers from contamination.

Laminar flow clean room products such as biological safety cabinets, fume hoods, flow hoods and clean benches. Fume hoods keep toxic vapors out of the working area. Biological safety cabinet can protect the specimen and the worker from biological contamination. Flow hoods either horizontal or vertical air streams that protect the specimen with their own contamination-free filtered air. They can be used whenever a controlled environment at the bench top level is required.

In the industries including the research, manufacturing, pharmaceutical, bioscience, aerospace and food processing industries, use laminar flow clean room hoods everyday. Below is some sample of products by Clean Air Products manufacturer:

Fume Hoods – Series 1411

Clean Air Products' fume hoods have several sizes and configurations. The flexibility allows their customers' needs to be satisfied with a minimum of compromise.For maximum chemical resistance, the fume hoods are fabricated by stainless steel, polypropylene or fire-retardant polypropylene. Safeguarding the operators was a major concern and high priority in the design of this fume hood. An extensive list of options is available to adapt each fume hood to its particular application.

Features of Fume Hoods

Designed for maximum chemical resistance
Available in stainless steel, white polypropylene or fire-retardant white polypropylene
Units are available in 3, 4, 5, 6, and 8 ft. widths and 30, 36, and 42 in. depths. Other sizes are available upon request
Units are available in 3, 4, 5, 6, and 8 ft. widths and 30, 36, and 42 in. depths. Other sizes are available upon request
Superior quality, excellent appearance, and ruggedness have been achieved through a safety-oriented design
An extensive list of options available to meet your application requirements

Laminar Flow Hoods Workstation – Series 301

Laminar Flow Hoods Workstation (Series 301) is a general-purpose, horizontal flow clean bench is suitable to many types of mechanical or processing work. It is designed to provide a Class 100 or Class 10 clean air environment ideally for laboratory work, manufacturing, testing, inspection and/or pharmaceutical operations.The clean HEPA-filtered air flows outward from the cabinet. This horizontal laminar flow air washes out particulates and protect from contamination by entering the clean work zone. The Laminar Flow Workstation features "clean edge" construction that puts the hood and table top in shear with the media edge of the HEPA filters. It will reducing turbulence along the sides of the hood, improves the laminar flow hoods, and prevents contamination infiltration around the perimeter of the hoods.

Features of Laminar Flow Hoods

FLEX DUCT provides a factory sealed clean laminar airflow system with simple front HEPA filter removal
HEPA filter 99.99% efficient
Motor speed infinitely variable with solid state controller
Protective grill for absolute filter
Fiberglass prefilter easily removable
Formica tabletop
Duplex outlet for auxiliary equipment
"Clean" edge air-shear of the absolute filter
Shipped fully assembled, ready for operation, certified to meet or exceed Class 100 conditions of Federal Standard 209E
Superior quality, excellent appearance, and ruggedness have been achieved through the use of new wraparound structural design
Vinclad steel or painted structural materials offer the ultimate in appearance and a surface resistant to abuse
Selected sizes and options UL listed

Clean Room Benches – Series 416

The 416VF Series of Clean Room Benches are a vertical laminar flow clean room benches designed to install on top of typical metro wire or eagle-type wire shelving. The Clean Room Benches Series 416HF are a horizontal laminar flow clean room bench unit designed to set on table top and blow horizontally. Clean Room Benches come in several sizes of 2 x 2 ft., 2 x 3 ft., 2 x 4 ft., and 2 x 6 ft.

Features of Clean Room Benches

Decorative white painted steel housing
Internal motorized filter unit for full filter coverage
Solid curtains on three sides
Strip door on front
2 ft. x 4ft. shelving size
120 V power cord

Clean Room Inflow Dust Containment Cabinet – Series 1522

The Series 1522 Clean Room inflow dust containment cabinet comes in several of sizes and styles. The features are depending on the design of unit you choose. The standard Series 1522 Clean Room Dust Containment Cabinet units build of painted steel. This finish is designed to be compatible with normal clean room environments. The Clean Room Dust Containment Cabinet system is patterned to draw air into the wall-mounted filters that filtered and discharged back into the space.Note: The Clean Room Dust Containment Cabinet system is not designed to work with flammable vapors, odors, or corrosives. Protective garments and respirators should be worn by personal to prevent exposure to materials being used within the system.

Features of Clean Room Inflow Dust Containment Cabinet

Acrylic hood
Standard prefilter provides efficiency of 40% by NBS Test Method using atmospheric dust or better; high efficiency filters available
Customized options available
99.99% filter efficiency on 0.3 Micron (standard) HEPA and on 0.12 Micron ULPA
Effective solution for mailroom protection, hazardous materials, and bio-safety cabinet applications
Requires very little maintenance to achieve continuous optimum performance

Clean Air Products has been designing and manufacturing high quality clean room hoods systems, clean room components, clean room equipment and clean room supplies for a broad range of clean room applications since 1969, including those in the semiconductor, biomedical, pharmaceutical and aerospace/military industries, among others. They can be contacted at 763.425.9122.

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Sunday, June 29, 2008

Clean Room Hoods & Other Facilities - maintenance and monitoring

Cleanliness of the clean room hoods must be maintained. We must have maintenance and cleaning schedule of the clean room hoods in daily, weekly and monthly basis. Regular environmental cleaning, monitoring and maintenance must be occurred to provide sterility and safety for patients receiving medications as well as the health care team who preparing the medications. Below are some ideas how to clean Laminar Airflow Hood (vertical and horizontal airflow hood) and other exercise of cleaning practice in clean room area.

Cleaning of Clean Room Hoods (Laminar Airflow Hoods; vertical and horizontal)

You can do cleaning of Laminar Airflow Hoods once a week or whenever spill occurs by using Conclikt cleaner. If possible, remove the pan and the vent covers. Use spray bottle to apply Conflikt cleaner to remove pieces as well as inside the hood. Wait for approximately 12 minutes to allow surfaces to soak. Wipe surfaces starting from back of the hood. The direction of wiping is from side to side towards the front opening of the hood. Use lint free gauze pads when wiping.

For any glass surfaces of clean room hoods, use water to avoid hazing of the glass. You also need to use isopropyl to apply to all surfaces. Wipe the surfaces from back to front of the hood and wiping from side to side in broad strokes. Allow surfaces for air dry without wiping. Depend on the pan and vent covers condition, you also required to replace it if needed.

Clean once a shift with isopropyl alcohol. Apply isopropyl alcohol to all surfaces. Wipe from back to front of hood wiping from side to side in broad strokes. Allow surfaces to air dry without wiping.

Cleanroom Maintenance: Trash, Waste and Cleaning of Surfaces

Collection and removal of trash, biohazard waste and cleaning of non-sterile surfaces are part of immediate maintenance in clean room area. The following events will occur on a scheduled basis and will be documented in the log adjacent to the clean room area.

You should put in daily schedule to clear and empty waste and replace liners. Cleanse laminar airflow hood and cleaning of non-sterile environment surfaces also in daily scheduled.

For weekly basis cleaning are removing biohazardodous waste, replace liner and/or receptacle. Cleaning of countertops, stool tops and other equipment (i.e pump) should be done in daily basis. Floor moping should be done twice a week, but subject to floor conditions. For cleaning of the walls, windows and doors is in monthly basis. Other exercise is doing monthly are cleaning and sanitize the bins.

Facilities Monitoring: Refrigerator, Freezer and Room Temperature Monitoring For those equipment that monitored by MadgeTech®: Temperature data will be downloaded monthly. The data must be printed and saved in proper file location. Each unit will be regulated for every six (6) months. For the units equipped with an audible alarm system will be tested once every 30 days to ensure proper function.

Corrective Action for Units Displaying Temperatures Outside of Range Designated:

1. For units with remote monitoring, an alarm will notify Facilities Management at OHSU if and when the temperature has gone out of predetermined range. Research Pharmacy Services personnel will be notified immediately via paging system or telephone.

2. In cases of an audible, non-remote monitored system, valuation of the unit will be made. Every effort will be made to find out the cause of alarm prior to movement of stock as outlined below.

3. In the event that the system is not functioning and it is suspected or confirmed that the unit is non-operational, immediately transfer all products to a similar, working, monitored unit in the department. Submit an inventory list to the broken unit that includes date and time the items were moved, a complete list and quantity of the items moved, and the location of the new storage space. Inform the RPS Pharmacist in Charge of the unit failure and inventory transfer.

4. Within 48-hour (2 working days) observation period will occur in case of unit malfunction. The temperature and conditions of the unit will be observed prior to return of inventory into the unit.

In any and all cases, the monitoring firm and study team will be notified in writing regarding the alarm, the cause and the status of study inventory.

Facilities Maintenance: Refrigerator and Freezer Maintenance, Calibration and Cleaning

1. Units equipped with an audible alarm system will be tested once every 30 days to ensure proper function.

2. The following USP temperature ranges will be maintained

Room Temperature - 20°C -25°C
Refrigerator - 2°C -8°C
-20 Freezer - -20°C - -10°C
-70C Freezer - ≤-70°C

The above exercise and practice to maintain the clean room hoods, maintain and monitor other facilities in the clean room area should be done in regular basis to ensure the clean environment in the work place.